induce apoptosis — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T5755	Aloesin		Tyrosinase
	Aloesin is a C-glycosylated chromone compound found in aloe (Liliaceae) that inhibits tyrosinase (IC50 = 0.9 mM), an enzyme responsible for catalyzing the first step of the conversion of tyrosine to melanin.		Tyrosinase
T5S0106	Peimisine	Ebeiensine	RAAS , AChR
	1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe...		RAAS , AChR
T5135	Flupentixol dihydrochloride	Fupentixol Dihydrochloride,Flupenthixol dihydrochloride,(E/Z)-Flupentixol Dihydrochloride	Dopamine Receptor
	Flupentixol dihydrochloride is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders.		Dopamine Receptor
TQ0134	Podocarpusflavone A		Topoisomerase
	Podocarpusflavone A is a DNA topoisomerase I inhibitor. It has moderated anti-proliferative activity induce cell apoptosis in MCF-7.		Topoisomerase
T3293	Apoptozole	Apoptosis Activator VII	Apoptosis , HSP
	Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.		Apoptosis , HSP
T22870	IPAG		Opioid Receptor
	IPAG is a potent σ-receptor antagonist (pKi=4.3). IPAG can induce cell apoptosis.		Opioid Receptor
T5352	GLYCODEOXYCHOLIC ACID		Others , Endogenous Metabolite
	Glycodeoxycholic Acid is a bile acid that induces severe pancreatitis in rats. It can induce the apoptosis of SMMC-7721 cells.		Others , Endogenous Metabolite
T67769	MPT0B014		Microtubule Associated
	MPT0B014 is a potent tubulin polymerization inhibitor. MPT0B014 can induce cancer cell apoptosis.		Microtubule Associated
T15337	Forodesine	BCX-1777,Immucillin-H	Others
	Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine is an orally active inhibitor of purine nucleoside phosphorylase (IC50s: 0.48 to 1.57 nM for human, mouse, rat, monkey, and dog PNP). It could i...		Others
T36013	Lysophosphatidylcholines	Lyso-Lecithins (egg)	Apoptosis
	Lysophosphatidylcholines (Lyso-Lecithins (egg)) are orally active lipids that induce cell damage and apoptosis, and induce demyelination. Lysophosphatidylcholines play a role in mediating inflammation, fibrosis, and canc...		Apoptosis
T9712	PF07104091	PF-07104091	CDK
	PF07104091 inhibits CDK2, which may lead to cell cycle arrest, induce apoptosis and inhibit tumor cell proliferation.		CDK
T6844	GGTI298 Trifluoroacetate	GGTI 298,GGTI 298 TFA salt	Apoptosis , Transferase , Ras
	GGTI298 Trifluoroacetate (GGTI 298 TFA salt) is a geranylgeranyltransferase I inhibitor with ability to arrest human tumor cells in the G1 phase of the cell cycle and induce apoptosis.		Apoptosis , Transferase , Ras
T20003	Acridone		Antibacterial , ABC
	Acridone could induce cell apoptosis, inhibited ABCG2 (ATP-binding cassette sub-family G member 2) protein, and adjusted hormone level.		Antibacterial , ABC
T7337	Kinetin riboside	N6-Furfuryladenosine	Apoptosis
	Kinetin riboside (N6-Furfuryladenosine) can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells(IC50 of 2.5 μM)		Apoptosis
T13476	β-Elemene	(-)-β-Elemene,Levo-β-elemene	Apoptosis
	β-Elemene (Levo-β-elemene) is a natural product isolated from Curcuma wenyujin, with an antitumor activity and induce cell apoptosis.		Apoptosis
TN1421	Bacopaside II		Apoptosis
	Bacopaside II is a potential anti-angiogenic agent, it can reduce endothelial cell migration and tubulogenesis and induce apoptosis.		Apoptosis
T7727	Se-Methylselenocysteine	Se MSC,SeMCys,MSeC,Se-MSC,SeMSC	BCL , IAP , Caspase
	Se-Methylselenocysteine (Se-MSC) is a potent chemopreventive agent in many test systems and has been shown to inhibit tumor promotion and induce apoptosis.		BCL , IAP , Caspase
T14846	Bz 423	BZ48	Apoptosis , BCL
	Bz 423 is a potent immunomodulator that induces apoptosis by activating Bax and Bak to induce mitochondrial outer membrane permeabilization and cytochrome c release.Bz 423 shows partial activity in a mouse model of lupus...		Apoptosis , BCL
TQ0089	Juglanin		Apoptosis , JNK , Autophagy
	Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.		Apoptosis , JNK , Autophagy
T5654	Musk ketone		Others
	Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.		Others